Who we are
We are dedicated to researching kidney diseases. Our team has a great enthusiasm to find out how kidney diseases develop. Our team is willing to challenge new technology to keep ourselves updated. We are well experienced in handling animal kidney disease models. To achieve precision medicine, our team is working on translational research with our own large biobank for human kidney tissue. We believe multi-omics analyses such as genomics, transcriptomics, epigenomics, metabolomics, and proteomics help to understand the underlying mechanism of kidney diseases.
Our Team
Projects
Molecular mechanism
of kidney disease
Omics analysis
at single-cell level
Metabolic changes in kidney disease
Genetic association with kidney disease
Contribution of altered tubules to kidney fibrosis
More and more
about kidney
We are open to Graduate students, International Students, Postdocs,
and Research assistants!
Please contact us!
Contact: tomorurira0220@gmail.com
Link of Interests
Always NU
Master and Doctoral Course
Nagoya University Graduate School of Medicine
Publications
NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury.
Doke T, Mukherjee S, Mukhi D, Dhillon P, Abedini A, Davis JG, Chellappa K, Chen B, Baur JA, Susztak K.
Nat Metab. 2023
Balzer MS, Doke T, Yang YW, Aldridge DL, Hu H, Mai H, Mukhi D, Ma Z, Shrestha R, Palmer MB, Hunter CA, Susztak K.
Nat Commun. 2022
Liu H, Doke T, Guo D, Sheng X, Ma Z, Park J, Vy HMT, Nadkarni GN, Abedini A, Miao Z, Palmer M, Voight BF, Li H, Brown CD, Ritchie MD, Shu Y, Susztak K.
Nat Genet. 2022
Doke T, Abedini A, Aldridge DL, Yang YW, Park J, Hernandez CM, Balzer MS, Shrestra R, Coppock G, Rico JMI, Han SY, Kim J, Xin S, Piliponsky AM, Angelozzi M, Lefebvre V, Siracusa MC, Hunter CA, Susztak K.
Nat Immunol. 2022
Genome-wide association studies identify the role of caspase-9 in kidney disease.
Doke T, Huang S, Qiu C, Sheng X, Seasock M, Liu H, Ma Z, Palmer M, Susztak K.
Sci Adv. 2021
Doke T, Huang S, Qiu C, Liu H, Guan Y, Hu H, Ma Z, Wu J, Miao Z, Sheng X, Zhou J, Cao A, Li J, Kaufman L, Hung A, Brown CD, Pestell R, Susztak K.
J Clin Invest. 2021